Always check the relevant regulatory demands before commencing a study involving human subjects. A good starting point here is this Research Guide's legal section .
Physical measurement instruments
If you are planning to use physical measurement instruments, such as thermometers, weight scales, or blood pressure meters, give due consideration to the instrument's required measurement properties, check that the instrument meets your accuracy requirements, and confirm that the measurement protocol complies with the quality assurance requirements. For ideas on how to tackle these issues, read this guideline .
Biomechanical Test Facilities
Medical Technology is equipped with a Biomechanical Testing Laboratory. Here, the effects of mechanical impacts (forces, impacts, pressures, etc.) on cells and tissues can be measured. The Biomechanical Testing Laboratory has a wide range of equipment, including an advanced Instron Tensile machine.
Looking for the best questionnaire? The Knowledgecenter Measurement Instruments offers researchers tailored advice and support in finding the most appropriate measurement instrument (or instruments) for a given purpose. It also designs and investigates the measurement properties of such instruments.
Radiology scans for research
Are you planning to use MRI, CT scans, or other imaging techniques? If so, contact the radiology department for details of the available options, relevant procedures, and costs.
The Advanced Imaging Lab offers high-speed imaging, high-contrast imaging, thermal imaging and infrared imaging for studies of the interactions of medical equipment being used in patients for the purpose of diagnostics and therapy. Click here for more details.
LABnet is a physiological testing facility at the department of Rehabilitation Medicine. LABnet features a walking lab, equipment for exercise tests and muscle function.
Are you conducting an investigator-initiated study? If so, be sure to visit the Clinical Research Bureau's website, for details of the steps that you need to take, as well as for help and advice. Do you know how to design a Case Report Form (CRF) that is compliant with official requirements, or how to create a CRF in Open Clinica? Open Clinica is a GCP compliant database that is available to VUmc researchers. Further details are available at the CRB site .
For details on how to perform an observational study, please refer to the EMGO+ quality handbook . It contains a wide range of guidelines on procedures for observational research.
Study Medication in clinical research
When conducting investigator-initiated drug research you always have to perform a feasibility analysis. You also have to take legislative details into account and the estimated time required to process the drug, as well as the overall application or usage of the drug. Preparing available drugs for clinical studies can be a very complex process, and may take up to 9 months. Accordingly, we recommend that you contact the Department of Experimental Pharmacy in an early stage in your project. Pharmacist Pierre Bet will discuss all of the necessary details pertaining to your planned research, including details of the study medication or any other pharmaceutical materials.
It is important that at least one researcher in the study team remains closely involved with all matters pertaining to the provision of medication. This individual should be the contact for the hospital and (if applicable) the pharmacist.
It is also important to know that agreements between the manufacturer of the study drug and the hospital must be recorded in a separate pharmacist's agreement, which can be attached to the clinical trial agreement (CTA).
For more details see Experimental Pharmacy VUmc and www.ccmo.nl or Onderzoek Met Geneesmiddelen METC VUmc (all in Dutch).