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Publications

June 2012

Verbakel WF, van Reij E, Ladenius-Lischer I, Cuijpers JP, Slotman BJ, Senan S.

Clinical Application of a Novel Hybrid Intensity-Modulated Radiotherapy Technique for Stage III Lung Cancer and Dosimetric Comparison With Four Other Techniques.

Int J Radiat Oncol Biol Phys. 2012 (83-2) : 297-303

We clinically implemented a novel hybrid IMRT (h-IMRT) technique that allowed plans to be produced quickly, and compared these plans with 4 other techniques.

May 2012

March 2012

Hanna GG, van Sörnsen de Koste JR, Dahele MR, Carson KJ, Haasbeek CJ, Migchielsen R, Hounsell AR, Senan S.

Defining Target Volumes for Stereotactic Ablative Radiotherapy of Early-stage Lung Tumours: A Comparison of Three-dimensional (18)F-fluorodeoxyglucose Positron Emission Tomography and Four-dimensional Computed Tomography.

Clin Oncol (R Coll Radiol). 2012 (Epub) : 0-0

Target volumes defined by positron emission tomography/computed tomography (PET/CT) are compared with those defined by four-dimensional CT and conventional ('three-dimensional') (18)F-fluorodeoxyglucose ((18)F-FDG) PET/CT.

Dahele M, Freeman M, Pearson S, Brade A, Cho BC, Hope A, Franks K, Purdie T, Bissonnette JP, Jaffray DA, Bezjak A, Sun A.

Early metabolic response evaluation after stereotactic radiotherapy for lung cancer: pilot experience with 18F-fluorodeoxyglucose positron emission tomography-computed tomography.

Clin Oncol (R Coll Radiol). 2011 (5) : 359-363

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Lind JS, Senan S, Smit EF

Pulmonary Toxicity After Bevacizumab and Concurrent Thoracic Radiotherapy Observed in a Phase I Study for Inoperable Stage III Non-Small-Cell Lung Cancer

J Clin Oncol. 2012 (8) : 30-104

We observed enhanced pulmonary parenchymal toxicity during treatment with bevacizumab concurrent with radiation, a finding that, to the best of our knowledge, has not been previously reported

Palma D, Lagerwaard F, Rodrigues G, Haasbeek C, Senan S.

Curative treatment of Stage I non-small-cell lung cancer in patients with severe COPD: stereotactic radiotherapy outcomes and systematic review.

Int J Radiat Oncol Biol Phys. 2012 (3) : 1149-1156

We studied outcomes after stereotactic body radiotherapy (SBRT) in patients with severe COPD, as defined by (GOLD) criteria, and performed a systematic review of the literature on outcomes after SBRT or surgery in these patients.

February 2012

Senan S, Postmus PE.

Reflections on the 14th World Conference on Lung Cancer: A European Perspective.

Oncologist. 2012 (Epub) : 0-0

Meeting report

Buis DR, Bot JC, Barkhof F, Knol DL, Lagerwaard FJ, Slotman BJ, Vandertop WP, van den Berg R.

The Predictive Value of 3D Time-of-Flight MR Angiography in Assessment of Brain Arteriovenous Malformation Obliteration after Radiosurgery.

AJNR Am J Neuroradiol. 2012 (2) : 232-238

The purpose of radiosurgery of bAVMs is complete angiographic obliteration of its nidus.

Kitty Huang a,b, Max Dahele c, Suresh Senan c, Matthias Guckenberger d, George B. Rodrigues a,b,e, Aaron Ward b, R. Gabriel Boldt a, David A. Palma a,b,⇑

Radiographic changes after lung stereotactic ablative radiotherapy (SABR) – Can we distinguish recurrence from fibrosis? A systematic review of the literature

Radiotherapy and Oncology 2012 (Epub) : 0-0

Can we distinguish recurrence from fibrosis?

January 2012

Bongers EM, Dahele MR, Slotman BJ, Senan S, Bot JC.

Proton stereotactic body radiation therapy for clinically challenging cases of centrally and superiorly located stage I non-small-cell lung cancer: in regards to register et Al. Int j radiat oncol biol phys 2011;80:1015-1022.

Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1015-22 2012 (82-1) : 492-492

We would like to take this opportunity to highlight an important point that the authors do not specifically address, namely the need for accurate OAR delineation.

December 2011

Bongers EM, Haasbeek CJ, Lagerwaard FJ, Slotman BJ, Senan S

Incidence and Risk Factors for Chest Wall Toxicity After Risk-Adapted Stereotactic Radiotherapy for Early-Stage Lung Cancer.

J Thorac Oncol. 2011 (12) : 2052-2057

We studied the incidence of chest wall pain (CWP) and rib fractures in patients with long-term follow-up.

November 2011

Vergeer MR, Doornaert PA, de Bree R, Leemans CR, Slotman BJ, Langendijk JA.

Postoperative elective nodal irradiation for squamous cell carcinoma of the head and neck: outcome and prognostic factors for regional recurrence.

Ann Oncol. 2011 (11) : 2489-2494

This study describes the results of elective irradiation in the N0 neck and tries to identify prognostic factors for regional recurrence.

Lagerwaard FJ, Verstegen NE, Haasbeek CJ, Slotman BJ, Paul MA, Smit EF, Senan S.

Outcomes of Stereotactic Ablative Radiotherapy in Patients with Potentially Operable Stage I Non-Small-Cell Lung Cancer.

Int J Radiat Oncol Biol Phys. 2011 (Epub) : 0-0

we studied outcomes after SABR in patients with potentially operable stage I NSCLC.

Verstegen NE, Lagerwaard FJ, Haasbeek CJ, Slotman BJ, Senan S

Outcomes of stereotactic ablative radiotherapy following a clinical diagnosis of stage I NSCLC: Comparison with a contemporaneous cohort with pathologically proven disease.

Radiother Oncol. 2011 (2) : 250-254

We studied outcomes in patients who underwent SABR after either a pathological (n=209) or clinical diagnosis (N=382).

October 2011

Hanna GG, Van Sörnsen De Koste JR, Carson KJ, O'Sullivan JM, Hounsell AR, Senan S.

Conventional 3D staging PET/CT in CT simulation for lung cancer: impact of rigid and deformable target volume alignments for radiotherapy treatment planning.

Br J Radiol. 2011 (1006) : 919-929

As staging PET/CT scans are increasingly available, we evaluated different methods for co-registration of staging PET/CT data to radiotherapy simulation (RTP) scans.

September 2011

Dahele M, Palma D, Lagerwaard F, Slotman B, Senan S.

Radiological changes after stereotactic radiotherapy for stage I lung cancer.

J Thorac Oncol. 2011 (7) : 1221-1228

The aim of this study is to describe the incidence, radiological severity, and long-term morphology of these changes.

August 2011

Le Péchoux C, Laplanche A, Faivre-Finn C, Ciuleanu T, Wanders R, Lerouge D, Keus R, Hatton M, Videtic GM, Senan S, Wolfson A, Jones R, Arriagada R, Quoix E, Dunant A; Prophylactic Cranial Irradiation (PCI) Collaborative Group.

Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01).

Ann Oncol. 2011 ( ) : 0-0

Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses

Dahele M, Senan S.

The Role of Stereotactic Ablative Radiotherapy for Early-Stage and Oligometastatic Non-small Cell Lung Cancer: Evidence for Changing Paradigms.

Cancer Res Treat. 2011 ( ) : 0-0

A compelling body of non-randomized evidence has established stereotactic ablative lung radiotherapy (SABR) as a standard of care for medically inoperable patients with peripheral early-stage non-small cell lung cancer (NSCLC).

July 2011

Felip E, Gridelli C, Baas P, Rosell R, Stahel R; Panel Members.

Metastatic non-small-cell lung cancer: consensus on pathology and molecular tests, first-line, second-line, and third-line therapy: 1st ESMO Consensus Conference in Lung Cancer; Lugano 2010.

Ann Oncol. 2011 (7) : 1507-1519

The consensus agreement on three of these areas: NSCLC pathology and molecular testing, the treatment of first-line, and second-line/third-line therapy in metastatic NSCLC are reported in this article.

Treasure T, Lang-Lazdunski L, Waller D, Bliss JM, Tan C, Entwisle J, Snee M, O'Brien M, Thomas G, Senan S, O'Byrne K, Kilburn LS, Spicer J, Landau D, Edwards J, Coombes G, Darlison L, Peto J; for the MARS trialists.

Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study.

Lancet Oncology 2011 ( ) : 0-0

The effects of extra-pleural pneumonectomy (EPP) on survival and quality of life in patients with malignant

June 2011

Doornaert P, Verbakel WF, Rietveld DH, Slotman BJ, Senan S.

Sparing the contralateral submandibular gland without compromising PTV coverage by using volumetric modulated arc therapy.

Radiation Oncology 2011 (6) : 0-0

Salivary gland function decreases after radiation doses of 39 Gy or higher.

Phernambucq EC, Palma DA, Vincent A, Smit EF, Senan S.

Time and dose-related changes in radiological lung density after concurrent chemoradiotherapy for lung cancer.

Lung Cancer 2011 (3) : 451-456

Radiation pneumonitis is an important cause of morbidity after concurrent thoracic chemoradiotherapy (CCRT).

Palma D, Lagerwaard F, Rodrigues G, Haasbeek C, Senan S.

Curative Treatment of Stage I Non-small-cell Lung Cancer in Patients with Severe COPD: Stereotactic Radiotherapy Outcomes and Systematic Review

Int J Radiat Oncol Biol Phys. 2011 (Epub) : 0-0

Patients with severe chronic obstructive pulmonary disease (COPD) have a high risk of lung cancer and of postsurgical complications.

May 2011

Louie AV, Rodrigues G, Hannouf M, Lagerwaard F, Palma D, Zaric GS, Haasbeek C, Senan S.

Withholding stereotactic radiotherapy in elderly patients with stage I non-small cell lung cancer and co-existing COPD is not justified: Outcomes of a markov model analysis

Radiother 2011 (99(2)) : 161-165

To model outcomes of SBRT versus best supportive care (BSC) in elderly COPD patients with stage I NSCLC

March 2011

Senan S, Cardenal F, Vansteenkiste J, Stigt J, Akyol F, De Neve W, Bakker J, Dupont JM, Scagliotti GV, Ricardi U, van Meerbeeck JP.

A randomized phase II study comparing induction or consolidation chemotherapy with cisplatin-docetaxel, plus radical concurrent chemoradiotherapy with cisplatin-docetaxel, in patients with unresectable locally advanced non-small-cell lung cancer.

Ann Oncol 2011 (22) : 553-558

In stage III non-small-cell lung cancer (NSCLC), the role of systemic chemotherapy preceding or following concurrent chemo-radiotherapy (CT-RT) is unclear.

February 2011

Treasure, T ; Senan, S

The Need for Randomized Trials in Mesothelioma: Let's Walk the Talk

Oncologist 2011 (16-3) : 261-263

Pleural mesothelioma; clinical trials

January 2011

Senan S, Palma D.

Stereotactic lung radiotherapy: do we need fiducial markers?

Ann Thorac Surg. 2011 2011 (Epub) : 0-0

Stereotactic lung radiotherapy: do we need fiducial markers?

December 2010

November 2010

Cuijpers JP, Verbakel WF, Slotman BJ, Senan S.

A novel simple approach for incorporation of respiratory motion in stereotactic treatments of lung tumors.

Radiother Oncol. 2010 (Epub) : 0-0

An internal target volume (ITV) is often used for incorporating tumor motion into radiotherapy planning but it overestimates the margins necessary for breathing motion.

October 2010

Ong CL, Palma D, Verbakel WF, Slotman BJ, Senan S.

Treatment of large stage I-II lung tumors using stereotactic body radiotherapy (SBRT): Planning considerations and early toxicity.

Radiother Oncol. 2010 (Epub) : 0-0

To study the dosimetric predictors of early clinical toxicity following SBRT in patients with lung tumors and planning target volumes (PTV) exceeding 80cm(3).

Hurkmans CW, van Lieshout M, Schuring D, van Heumen MJ, Cuijpers JP, Lagerwaard FJ, Widder J, van der Heide UA, Senan S.

Quality Assurance of 4D-CT Scan Techniques in Multicenter Phase III Trial of Surgery Versus Stereotactic Radiotherapy (Radiosurgery Or Surgery for operable Early stage (Stage 1A) non-small-cell Lung cancer [ROSEL] Study).

Int J Radiat Oncol Biol Phys. 2010 (Epub) : 0-0

To determine the accuracy of four-dimensional computed tomography (4D-CT) scanning techniques in institutions participating in a Phase III trial of surgery vs. stereotactic radiotherapy (SBRT) for lung cancer.

September 2010

Lind JS, Lagerwaard FJ, Smit EF, Postmus PE, Slotman BJ, Senan S.

Time for reappraisal of extracranial treatment options?: synchronous brain metastases from nonsmall cell lung cancer.

Cancer 2010 (Epub) : 0-0

The optimal treatment of the primary tumor in patients with brain metastases (BM) from newly diagnosed nonsmall cell lung cancer (NSCLC) remains unclear.

July 2010

Ong C, Verbakel WF, Cuijpers JP, Slotman BJ, Senan S.

Dosimetric Impact of Interplay Effect on RapidArc Lung Stereotactic Treatment Delivery.

Int J Radiat Oncol Biol Phys. 2010 (Epub ahead of print) : 0-0

Volumetric modulated arc therapy (RapidArc; Varian Medical Systems, Palo Alto, CA) allows fast delivery of stereotactic radiotherapy for Stage I lung tumors.

van Dam IE, van Sörnsen de Koste JR, Hanna GG, Muirhead R, Slotman BJ, Senan S.

Improving target delineation on 4-dimensional CT scans in stage I NSCLC using a deformable registration tool.

Radiother Oncol. 2010 (96) : 67-72

Improving target delineation on 4-dimensional CT scans in stage I NSCLC using a deformable registration tool.

June 2010

Palma DA, Senan S, Haasbeek CJ, Verbakel WF, Vincent A, Lagerwaard F.

Radiological and Clinical Pneumonitis after Stereotactic Lung Radiotherapy: A Matched Analysis of Three-dimensional Conformal and Volumetric-modulated Arc Therapy Techniques.

Int J Radiat Oncol Biol Phys. 2010 (Epub ahead of print) : 0-0

Radiological and Clinical Pneumonitis after Stereotactic Lung Radiotherapy: A Matched Analysis of Three-dimensional Conformal and Volumetric-modulated Arc Therapy Techniques.

Eppinga W, Lagerwaard F, Verbakel W, Slotman B, Senan S.

Volumetric modulated arc therapy for advanced pancreatic cancer.

Strahlenther Onkol. 2010 (Epub) : 0-0

Volumetric modulated arc therapy for advanced pancreatic cancer.

Malinowski KT, Pantarotto JR, Senan S, McAvoy TJ, D'Souza WD.

Inferring positions of tumor and nodes in Stage III lung cancer from multiple anatomical surrogates using four-dimensional computed tomography.

Int J Radiat Oncol Biol Phys. 2010 (Epub) : 0-0

Inferring positions of tumor and nodes in Stage III lung cancer from multiple anatomical surrogates using four-dimensional computed tomography.

Dahele M, Senan S.

Radiation oncology: overview and recent advances.

J R Coll Physicians Edinb. 2010 (40(2)) : 136-143

Most patients with cancer will be looked after by a diverse team made up of members from community- and hospital-based services.

Palma DA, Tyldesley S, Sheehan F, Mohamed IG, Smith S, Wai E, Murray N, Senan S.

Stage I non-small cell lung cancer (NSCLC) in patients aged 75 years and older: does age determine survival after radical treatment?

J Thorac Oncol. 2010 (5) : 818-824

Stage I non-small cell lung cancer (NSCLC) in patients aged 75 years and older: does age determine survival after radical treatment?

Luttjeboer M, Lafleur MV, Kwidama ZJ, Van Rijn J, Van Den Berg J, Slotman BJ, Kaspers GJ, Cloos J.

Strategies for the analysis of in vitro radiation sensitivity and prediction of interaction with potential radiation modifying agents.

Int J Radiat Biol. 2010 (86) : 458-466

Strategies for the analysis of in vitro radiation sensitivity and prediction of interaction with potential radiation modifying agents.

Schoonbeek A, Monshouwer R, Hanssens P, Raaijmakers E, Nowak P, Marijnissen JP, Lagerwaard FJ, Cuijpers JP, Vonk EJ, van der Maazen RW.

Intracranial radiosurgery in the Netherlands. A planning comparison of available systems with regard to physical aspects and workload.

Technol Cancer Res Treat. 2010 (9) : 279-290

Different planning and treatment systems for intracranial stereotactic radiosurgery available in the Netherlands are compared.

May 2010

April 2010

Doornaert P, Verbakel WF, Bieker M, Slotman BJ, Senan S.

RapidArc Planning and Delivery in Patients with Locally Advanced head-and-neck Cancer Undergoing Chemoradiotherapy.

Int J Radiat Oncol Biol Phys. 2010 (Epub ahead of print) : 0-0

RapidArc Planning and Delivery in Patients with Locally Advanced head-and-neck Cancer Undergoing Chemoradiotherapy.

Mandl ES, Meijer OW, Slotman BJ, Vandertop WP, Peerdeman SM.

Stereotactic radiation therapy for large vestibular schwannomas.

Radiother Oncol. 2010 (95) : 94-98

Stereotactic radiation therapy for large vestibular schwannomas.

March 2010

Buis DR, Meijer OW, van den Berg R, Lagerwaard FJ, Bot JC, Slotman BJ, Vandertop WP.

Clinical outcome after repeated radiosurgery for brain arteriovenous malformations.

Radiother Oncol. 2010 (Epub ) : 0-0

Clinical outcome after repeated radiosurgery for brain arteriovenous malformations.

February 2010

Senan S, Lagerwaard F.

Stereotactic radiotherapy for stage I lung cancer: current results and new developments.

Cancer Radiother. 2010 (Epub) : 0-0

Stereotactic radiotherapy for stage I lung cancer: current results and new developments.

Vergeer MR, Doornaert PA, Jonkman A, Kaanders JH, den Ende PL, de Jong MA, Rene Leemans C, Slotman BJ, Langendijk JA.

Ipsilateral Irradiation for Oral and Oropharyngeal Carcinoma Treated With Primary Surgery and Postoperative Radiotherapy.

Int J Radiat Oncol Biol Phys. 2010 (Epub) : 0-0

Ipsilateral Irradiation for Oral and Oropharyngeal Carcinoma Treated With Primary Surgery and Postoperative Radiotherapy.

Kuijper IT, Dahele M, Senan S, Verbakel WF.

Volumetric modulated arc therapy versus conventional intensity modulated radiation therapy for stereotactic spine radiotherapy: a planning study and early clinical data.

Radiother Oncol. 2010 (Epub) : 0-0

Volumetric modulated arc therapy versus conventional intensity modulated radiation therapy for stereotactic spine radiotherapy: a planning study and early clinical data.

January 2010

Haasbeek CJ, Lagerwaard FJ, Antonisse ME, Slotman BJ, Senan S.

Stage I nonsmall cell lung cancer in patients aged > or =75 years: outcomes after stereotactic radiotherapy.

Cancer 2010 (116) : 406-414

Stage I nonsmall cell lung cancer in patients aged > or =75 years: outcomes after stereotactic radiotherapy.

November 2009

Slotman BJ.

Radiotherapy for extensive stage small cell lung cancer.

Front Radiat Ther Oncol. 2009 (Epub) : 0-0

Radiotherapy for extensive stage small cell lung cancer.

October 2009

Wu K, Ung YC, Hornby J, Freeman M, Hwang D, Tsao MS, Dahele M, Darling G, Maziak DE, Tirona R, Mah K, Wong CS.

PET CT thresholds for radiotherapy target definition in non-small-cell lung cancer: how close are we to the pathologic findings?

Int J Radiat Oncol Biol Phys. 2009 (Epub) : 0-0

Optimal target delineation threshold values for positron emission tomography (PET) and computed tomography (CT) radiotherapy planning is controversial...

September 2009

Wu WC, Chan CL, Wong YW, Cuijpers JP.

A study on the influence of breathing phases in intensity-modulated radiotherapy of lung tumours using four-dimensional CT.

Br J Radiol. 2009 (Epub) : 0-0

During gated intensity-modulated radiotherapy (IMRT) treatment for patients with inoperable non-small cell lung cancer (NSCLC), the end-expiration (EE) phase of respiratory is more stable...

Hurkmans CW, Cuijpers JP, Lagerwaard FJ, Widder J, van der Heide UA, Schuring D, Senan S.

Dosimetric evaluation of heterogeneity corrections for RTOG 0236: stereotactic body radiotherapy of inoperable Stage I-II non-small-cell lung cancer. In reply to Dr. Xiao et al.

Int J Radiat Oncol Biol Phys. 2009 (75) : 318-318

Dosimetric evaluation of heterogeneity corrections for RTOG 0236: stereotactic body radiotherapy of inoperable Stage I-II non-small-cell lung cancer. In reply to Dr. Xiao et al.

August 2009

Hilverda K, Bosma I, Heimans JJ, Postma TJ, Peter Vandertop W, Slotman BJ, Buter J, Reijneveld JC, Klein M.

Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings.

J Neurooncol. 2009 (Epub) : 0-0

Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings.

July 2009

Phernambucq EC, Spoelstra FO, Paul MA, Senan S, Melissant CF, Postmus PE, Smit EF.

Evaluation of a treatment strategy for optimising preoperative chemoradiotherapy in stage III non-small-cell lung cancer.

Eur J Cardiothorac Surg. 2009 (Epub) : 0-0

Evaluation of a treatment strategy for optimising preoperative chemoradiotherapy in stage III non-small-cell lung cancer.

Lagerwaard FJ, van der Hoorn EA, Verbakel WF, Haasbeek CJ, Slotman BJ, Senan S.

Whole-brain radiotherapy with simultaneous integrated boost to multiple brain metastases using volumetric modulated arc therapy.

Int J Radiat Oncol Biol Phys. 2009 (Epub) : 0-0

Whole-brain radiotherapy with simultaneous integrated boost to multiple brain metastases using volumetric modulated arc therapy.

June 2009

Verbakel WF, Senan S, Cuijpers JP, Slotman BJ, Lagerwaard FJ.

Rapid delivery of stereotactic radiotherapy for peripheral lung tumors using volumetric intensity-modulated arcs.

Radiother Oncol. 2009 (Epub) : 0-0

Rapid delivery of stereotactic radiotherapy for peripheral lung tumors using volumetric intensity-modulated arcs.

Lagerwaard FJ, Meijer OW, van der Hoorn EA, Verbakel WF, Slotman BJ, Senan S.

Volumetric modulated arc radiotherapy for vestibular schwannomas.

Int J Radiat Oncol Biol Phys. 2009 (74) : 610-615

Volumetric modulated arc radiotherapy for vestibular schwannomas.

May 2009

Vokes EE, Senan S, Treat JA, Iscoe NA.

PROCLAIM: A phase III study of pemetrexed, cisplatin, and radiation therapy followed by consolidation pemetrexed versus etoposide, cisplatin, and radiation therapy followed by consolidation cytotoxic chemotherapy of choice in locally advanced stage III ...

Clin Lung Cancer. 2009 (3) : 193-198

This clinical trial summary provides the background and rationale for a randomized trial examining the benefits of pemetrexed/ cisplatin chemotherapy combined with radiation followed by consolidation pemetrexed ...

Veenhof AA, Bloemena E, Engel AF, van der Peet DL, Meijer OW, Cuesta MA.

The relationship of histological tumor regression grade (TRG) and two different time intervals to surgery following radiation therapy for locally advanced rectal cancer.

Int J Colorectal Dis. 2009 (Epub) : 0-0

The objective of this study was to assess the effect of two different time intervals between radiation therapy and surgery for rectal cancer on the histological tumor regression grade (TRG) in the resected specimen...

Verbakel WF, Cuijpers JP, Hoffmans D, Bieker M, Slotman BJ, Senan S.

Volumetric intensity-modulated arc therapy vs. conventional IMRT in head-and-neck cancer: a comparative planning and dosimetric study.

Int J Radiat Oncol Biol Phys. 2009 (74) : 252-259

Volumetric intensity-modulated arc therapy vs. conventional IMRT in head-and-neck cancer: a comparative planning and dosimetric study.

March 2009

Spoelstra FO, Pantarotto JR, van Sörnsen de Koste JR, Slotman BJ, Senan S.

Role of adaptive radiotherapy during concomitant chemoradiotherapy for lung cancer: analysis of data from a prospective clinical trial.

Int J Radiat Oncol Biol Phys. 2009 (Epub) : 0-0

Role of adaptive radiotherapy during concomitant chemoradiotherapy for lung cancer: analysis of data from a prospective clinical trial.

Spoelstra FO, van Sörnsen de Koste JR, Vincent A, Cuijpers JP, Slotman BJ, Senan S.

An evaluation of two internal surrogates for determining the three-dimensional position of peripheral lung tumors.

Int J Radiat Oncol Biol Phys. 2009 (Epub) : 0-0

An evaluation of two internal surrogates for determining the three-dimensional position of peripheral lung tumors.

Verbakel WF, Senan S, Lagerwaard FJ, Cuijpers JP, Slotman BJ.

Comments on 'Single-Arc IMRT?'.

Phys Med Biol. 2009 (Epub) : 0-0

Comments on 'Single-Arc IMRT?'.

Lind JS, Lagerwaard FJ, Smit EF, Senan S.

Phase I study of concurrent whole brain radiotherapy and erlotinib for multiple brain metastases from non-small-cell lung cancer.

Int J Radiat Oncol Biol Phys. 2009 (Epub) : 0-0

Phase I study of concurrent whole brain radiotherapy and erlotinib for multiple brain metastases from non-small-cell lung cancer.

Hoefnagels FW, Lagerwaard FJ, Sanchez E, Haasbeek CJ, Knol DL, Slotman BJ, Vandertop WP.

Radiological progression of cerebral metastases after radiosurgery: assessment of perfusion MRI for differentiating between necrosis and recurrence.

J Neurol. 2009 (Epub) : 0-0

Radiological progression of cerebral metastases after radiosurgery: assessment of perfusion MRI for differentiating between necrosis and recurrence.

February 2009

Haasbeek CJ, Lagerwaard FJ, de Jaeger K, Slotman BJ, Senan S.

Outcomes of stereotactic radiotherapy for a new clinical stage I lung cancer arising postpneumonectomy.

Cancer 2009 (115) : 587-594

Outcomes of stereotactic radiotherapy for a new clinical stage I lung cancer arising postpneumonectomy.

January 2009

Langendijk JA, Doornaert P, Rietveld DH, Verdonck-de Leeuw IM, Leemans CR, Slotman BJ.

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

Radiother Oncol. 2009 (Epub) : 0-0

A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer.

Hurkmans CW, Cuijpers JP, Lagerwaard FJ, Widder J, van der Heide UA, Schuring D, Senan S.

Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study.

Radiat Oncol. 2009 (4) : 0-0

Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study.

December 2008

Vergeer MR, Doornaert PA, Rietveld DH, Leemans CR, Slotman BJ, Langendijk JA.

Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program.

Int J Radiat Oncol Biol Phys. 2008 (Epub) : 0-0

Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program.

Pantarotto JR, Piet AH, Vincent A, van Sörnsen de Koste JR, Senan S.

Motion analysis of 100 mediastinal lymph nodes: potential pitfalls in treatment planning and adaptive strategies.

Int J Radiat Oncol Biol Phys. 2008 (Epub) : 0-0

Motion analysis of 100 mediastinal lymph nodes: potential pitfalls in treatment planning and adaptive strategies.

Slotman BJ, Mauer ME, Bottomley A, Faivre-Finn C, Kramer GW, Rankin EM, Snee M, Hatton M, Postmus PE, Collette L, Senan S.

Prophylactic cranial irradiation in extensive disease small-cell lung cancer: short-term health-related quality of life and patient reported symptoms: results of an international Phase III randomized controlled trial by the EORTC Radiation Oncology and Lung Cancer Groups.

J Clin Oncol. 2008 (Epub) : 0-0

Prophylactic cranial irradiation in extensive disease small-cell lung cancer: short-term health-related quality of life and patient reported symptoms: results of an international Phase III randomized controlled trial by the EORTC Radiation Oncology and Lung Cancer Groups.

November 2008

Van der Geld YG, van Triest B, Verbakel WFAR, van Sörnsen de Koste JR, Senan S, Slotman BJ, Lagerwaard FJ.

Evaluation of four-dimensional computed tomography-based intensity-modulated techniques and respiratory-gated radiotherapy techniques for pancreatic carcinoma.

Int J Radiat Oncol Biol Phys 2008 (72) : 1215-1220

Evaluation of four-dimensional computed tomography-based intensity-modulated techniques and respiratory-gated radiotherapy techniques for pancreatic carcinoma.

September 2008

Haasbeek CJ, Slotman BJ, Senan S.

Radiotherapy for lung cancer: Clinical impact of recent technical advances.

Lung Cancer 2008 (64) : 0-0

Radiotherapy for lung cancer: Clinical impact of recent technical advances.

August 2008

Langendijk JA, Doornaert P, Verdonck-de Leeuw IM, Leemans CR, Aaronson NK, Slotman BJ.

Impact of late treatment-related toxicity on quality of life among patients with head an neck cancer treated with Radiotherapy.

J Clin Oncol 2008 (26) : 3770-3776

Impact of late treatment-related toxicity on quality of life among patients with head an neck cancer treated with Radiotherapy.

July 2008

June 2008

Haasbeek CJA, Spoelstra FOB, Lagerwaard FJ, van Sörnsen de Koste JR, Cuijpers JP, Slotman BJ, Senan S.

Impact of audio-coaching on the position of lung tumors

Int J Radiat Oncol Biol Phys 2008 (71) : 1118-1123

Impact of audio-coaching on the position of lung tumors

Van der Weide L, van Sörnsen de Koste JR, Lagerwaard FJ, van Triest , Slotman BJ, Senan S.

Analysis of carina position as a surrogate marker for delivering phase-gated radiotherapy

Int J Radiat Oncol Biol Phys 2008 (71) : 1111-1117

Analysis of carina position as a surrogate marker for delivering phase-gated radiotherapy

De Langen AJ, Klabbers B, Boellaard R, Spreeuwenberg MD, Slotman BJ, de Bree R, Smit EF, Hoekstra OS, Lammertsma AA

Reproducibility of quantitative (18)F-3’-deoxy-3’-fluorothymidine measurement using positron emission tomography

Eur J Nucl Med Mol Imaging 2008 (2008) : 0-0

Reproducibility of quantitative (18)F-3’-deoxy-3’-fluorothymidine measurement using positron emission tomography

May 2008

Meijer OWM, Vandertop WP, Lagerwaard FJ, Slotman BJ.

Linear accelerator-based stereotactic radiosurgery for bilateral vestibular Schwannomas in patients with neurofibromatosis Type 2.

Neurosurg 2008 (62) : 37-43

Linear accelerator-based stereotactic radiosurgery for bilateral vestibular Schwannomas in patients with neurofibromatosis Type 2.

March 2008

Spoelstra FO, van Sörnsen de Koste JR, Cuijpers JP, Lagerwaard FJ, Slotman BJ, Senan S.

Analysis of reproducibility of respiration-triggered gated Radiotherapy for lung tumors

Radiother Oncol 2008 (87) : 59-64

Analysis of reproducibility of respiration-triggered gated Radiotherapy for lung tumors

Mauer M, Bottomley A, Colette L, Slotman BJ.

Palliative-care trials: How best to publish findings?

Lancet Oncol 2008 (9) : 411-412

Palliative-care trials: How best to publish findings?

February 2008

Meijer OWM, Weijmans EJ, Knol DL, Slotman BJ, Barkhof F, Vandertop WP, Castelijns JA

Tumor-volume changes after radiosurgery for vestibular Schwannoma: Implications for follow-up MR imaging protocol

Am J Neuroradiol 2008 (29) : 906-910

Tumor-volume changes after radiosurgery for vestibular Schwannoma: Implications for follow-up MR imaging protocol

January 2008

Haasbeek CJA, Senan S, Smit EF, Paul MA, Slotman BJ, Lagerwaard FJ.

Critical review of non-surgical treatment options for stage I non-small cell lung cancer

Oncologist 2008 (13) : 309-319

Critical review of non-surgical treatment options for stage I non-small cell lung cancer

December 2007

Lagerwaard FJ, Haasbeek CJ, Smit EF, Slotman BJ, Senan S.

Outcomes of Risk-Adapted Fractionated Stereotactic Radiotherapy for Stage I Non-Small-Cell Lung Cancer

Int J Radiat Oncol Biol Phys. 2007 (Epub ahead of print) : 0-0

High local control rates can be achieved using stereotactic radiotherapy in Stage I non-small-cell lung cancer (NSCLC), but reports have suggested that toxicity may be of concern.

November 2007

Molthoff CF, Klabbers BM, Berkhof J, Felten JT, van Gelder M, Windhorst AD, Slotman BJ, Lammertsma AA.

Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2'-deoxy-2'-[(18)F]fluoro-D: -glucose (FDG) and 3'-[ (18)F]fluoro-3'-deoxythymidine (FLT).

Mol Imaging Biol. 2007 (9(6)) : 340-347

Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2'-deoxy-2'-[(18)F]fluoro-D: -glucose (FDG) and 3'-[ (18)F]fluoro-3'-deoxythymidine (FLT).

Jellema AP, Slotman BJ, Doornaert P, Leemans CR, Langendijk JA.

Impact of radiation-induced xerostomia on quality of life after primary radiotherapy among patients with head and neck cancer

Int J Radiat Oncol Biol Phys. 2007 (69(3)) : 751-760

PURPOSE: To investigate the impact of xerostomia on overall quality of life (QoL) outcome and related dimensions among head and neck cancer patients treated with primary radiotherapy.

October 2007

Senan S, Arik S.

Global robust stability of bidirectional associative memory neural networks with multiple time delays

IEEE Trans Syst Man Cybern B Cybern. 2007 (37(5)) : 1375-1381

This correspondence presents a sufficient condition for the existence, uniqueness, and global robust asymptotic stability of the equilibrium point for bidirectional associative memory neural networks with discrete time delays.

Jellema AP, Slotman BJ, Doornaert P, Leemans CR, Langendijk JA.

Unilateral versus bilateral irradiation in squamous cell head and neck cancer in relation to patient-rated xerostomia and sticky saliva

Radiother Oncol. 2007 (85(1)) : 83-89

BACKGROUND AND PURPOSE: To investigate the association between radiation technique with patient-rated moderate and severe xerostomia and sticky saliva.

Kunst PW, Lee P, Paul MA, Senan S, Smit EF.

Restaging of mediastinal nodes with transbronchial needle aspiration after induction chemoradiation for locally advanced non-small cell lung cancer

J Thorac Oncol. 2007 (2(10)) : 912-915

Selecting the appropriate treatment strategy for patients with locally advanced non-small cell carcinoma (NSCLC) is of utmost importance to determine patient outcome.

August 2007

July 2007

Senan S.

Staging nodal disease in non-small cell lung cancer: implications for radiation therapy.

J Thorac Oncol. null (2(7)) : 585-587

null

June 2007

May 2007

April 2007

León X, López M, Piñeiro Z, Langendijk JA, Leemans CR, Quer M.

External validation of a risk group defined by recursive partitioning analysis in patients with head and neck carcinoma treated with surgery and postoperative radiotherapy.

Head Neck 2007 (29(9)) : 815-821

Several clinical trials have proved that concurrent chemoradiotherapy is more efficacious than radiotherapy alone among high-risk patients with head and neck squamous cell carcinoma (HNSCC) who undergo surgery.

March 2007

January 2007

Lagerwaard FJ, Senan S.

Lung cancer: intensity-modulated radiation therapy, four-dimensional imaging and mobility management.

Front Radiat Ther Oncol. 2007 (40) : 239-252

null

November 2006

Vandertop WP, Lagerwaard FJ.

Comment on: Case 21-2006: a man with left-side facial pain.

N Engl J Med. 2006 (355 (22)) : 2375-2376

Comment on: Case 21-2006: a man with left-side facial pain.

van der Geld YG, Lagerwaard FJ, van Sörnsen de Koste JR, Cuijpers JP, Slotman BJ, Senan S.

Reproducibility of target volumes generated using uncoached 4-dimensional CT scans for peripheral lung cancer.

Radiation Oncology 2006 (1) : 0-0

4-dimensional CT (4DCT) scans are increasingly used to account for mobility during radiotherapy planning.

October 2006

September 2006

Craanen ME, van Triest B, Verheijen RH, Mulder CJ.

Thalidomide in refractory haemorrhagic radiation induced proctitis.

Gut. 2006 (55(9)) : 1371-1372

naw

August 2006

Smid EJ, Stoter TR, Bloemena E, Lafleur MV, Leemans CR, van der Waal I, Slotman BJ, Langendijk JA.

The importance of immunohistochemical expression of EGFr in squamous cell carcinoma of the oral cavity treated with surgery and postoperative radiotherapy.

Int J Radiat Oncol Biol Phys. 2006 (65(5)) : 1323-1329

The aim of this study was to investigate the prognostic significance of epidermal growth factor (EGFr) expression in oral cavity squamous cell carcinoma (OCSCC) treated with curative surgery and postoperative radiotherapy.

July 2006

April 2006

March 2006

Underberg RW, Lagerwaard FJ, van Tinteren H, Cuijpers JP, Slotman BJ, Senan S.

Time trends in target volumes for stage I non-small-cell lung cancer after stereotactic radiotherapy.

Int J Radiat Oncol Biol Phys. 2006 (64(4)) : 1221-1228

PURPOSE: To identify potential time trends in target volumes and tumor mobility after stereotactic radiotherapy (SRT) for Stage I non-small-cell lung cancer.

Pos FJ, Hart G, Schneider C, Sminia P.

Radical radiotherapy for invasive bladder cancer: What dose and fractionation schedule to choose?

Int J Radiat Oncol Biol Phys. 2006 (64(4)) : 1168-1173

PURPOSE: To establish the alpha/beta ratio of bladder cancer from different radiotherapy schedules reported in the literature and provide guidelines for the design of new treatment schemes.

Baas P, Belderbos JS, Senan S, Kwa HB, van Bochove A, van Tinteren H, Burgers JA, van Meerbeeck JP.

Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: a Dutch multicenter phase II study.

Br J Cancer 2006 (94(5)) : 625-630

To improve the prognosis of limited stage small cell lung cancer (LS-SCLC) the addition of concurrent thoracic radiotherapy to a platinum-containing regimen is important

February 2006

January 2006

van der Kleij, Sminia P.

Neuroblastoma

Handbook on Hyperbaric Medicine 2006 (D. Mathieu (Ed.). Springer, Dordrecht) : 469-475

N.b.

Slotman BJ, Solberg T, Wurm R, Verellen D.

Introduction In Extracranial Stereotactic Radiotherapy and radiosurgery.

Taylor & Francis; New York 2006 (x) : 1-4

N.b.

Slotman BJ, Solberg TD, and Verellen D (eds.).

Extracranial stereotactic radiotherapy and radiosurgery.

Taylor & Francis, New York USA 2006 (ISBN 08247 2679) : 1-368

N.b.

Feng-Ming K, Bradley JD, Martel M, Senan S.

Cancers of the Thorax.

"Treatment Planning in Radiation Oncology" 2006 (nb) : 0-0

naw

December 2005

November 2005

Jellema AP, Doornaert P, Slotman BJ, Leemans CR, Langendijk JA.

Does radiation dose to the salivary glands and oral cavity predict patient-rated xerostomia and sticky saliva in head and neck cancer patients treated with curative radiotherapy?

Radiother. Oncol. 2005 (77 (2)) : 164-171

BACKGROUND AND PURPOSE: To investigate the association between the mean salivary gland and oral cavity dose, with patient-rated moderate and severe xerostomia and sticky saliva.

October 2005

Sminia P, Mayer R, van der Kleij A, Feldmeier J.

Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy

Int J Radiat Oncol Biol Phys. 63(2) (649) : 650-0

In regard to Anscher et al. (Int J Radiat Oncol Biol Phys 2005;62:255-259).

September 2005

Borggreven PA, Verdonck-de Leeuw I, Langendijk JA, Doornaert P, Koster MN, de Bree R, Leemans CR.

Speech outcome after surgical treatment for oral and oropharyngeal cancer: a longitudinal assessment of patients reconstructed by a microvascular flap.

Head Neck 2005 (27(9)) : 785-793

BACKGROUND: The aim of the study was to analyze speech outcome for patients with advanced oral/oropharyngeal cancer treated with reconstructive surgery and adjuvant radiotherapy.

August 2005

June 2005

Slotman BJ, Cottier B, Bentzen SM, Heeren G, Lievens Y, van den Bogaert W.

Overview of national guidelines for infrastructure and staffing of radiotherapy. ESTRO-QUARTS: work package 1.

Radiother Oncol. 2005 (75(3)) : 349-354

The aim of this study was to collect the available guidelines for infrastructure and staffing throughout Europe and to develop general guidelines.

Underberg RW, Lagerwaard FJ, Slotman BJ, Cuijpers JP, Senan S.

Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: an analysis of 4DCT datasets.

Int J Radiat Oncol Biol Phys. 2005 (62(2)) : 554-560

PURPOSE: High local control rates have been reported with stereotactic radiotherapy (SRT) for Stage I non-small-cell lung cancer...

May 2005

April 2005

Borggreven PA, Kuik DJ, Langendijk JA, Doornaert P, de Bree R, Leemans CR.

Severe comorbidity negatively influences prognosis in patients with oral and oropharyngeal cancer after surgical treatment with microvascular reconstruction.

Oral Oncol 2005 (41(4)) : 358-364

The aim of the study was to investigate the possible impact of comorbidity on survival of patients undergoing composite resection and microvascular reconstruction for oral/oropharyngeal cancer.

March 2005

February 2005

January 2005

Slotman BJ, Senan S.

Image-guided radiotherapy.

Gamma 2005 (55) : 20-24

N.b.

Senan S, Slotman BJ.

Clinical use of four-dimensional computed tomography scans

Eur Oncol Review 2005 (1) : 68-71

N.b.

Slotman BJ, Senan S.

Bewegende tumoren bestralen.

Med Contact 2005 (60) : 140-143

N.b.

Senan S, Lagerwaard FJ.

The role of radiotherapy in non-small-cell lung cancer.

Ann Oncol. 2005 (16 Suppl 2) : 223-228

The role of radiotherapy in non-small-cell lung cancer.

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